Actinic keratosis (AK), rough, scaly patches caused by long-term sun exposure, can become precancerous if left untreated. At Pure Dermatology Cosmetic and Hair Center in Newport Beach, Orange County, our dermatologists offer Photodynamic Therapy (PDT), a safe and effective in-office treatment that targets sun-damaged skin and reduces the appearance of actinic keratoses while protecting long-term skin health.
PDT is ideal for treating widespread areas of sun-damage and early skin changes before they progress.
What Is Actinic Keratosis (AK)?
Actinic keratoses are rough, dry, or scaly patches that develop on sun-exposed areas such as the:
- Face
- Scalp
- Arms
- Hands
- Neck
They usually feel like sandpaper and may be pink, red, or brownish in color. Because AKs are caused by ultraviolet damage from sun exposure or tanning beds, they’re most common in fair-skinned individuals and outdoor enthusiasts.
Left untreated, some actinic keratoses have the potential to progress to squamous cell carcinoma, a type of skin cancer, making early treatment essential.
What Is Photodynamic Therapy (PDT)?
Photodynamic Therapy (PDT) combines a photosensitizing medication with a specialized light source to selectively treat sun-damaged skin and AK lesions.
Here’s how it works:
- A topical photosensitizing solution is applied to the affected areas.
- Skin absorbs the solution over a period of time.
- A targeted light activates the medication, triggering a reaction that destroys abnormal cells while sparing healthy tissue.
PDT treats both visible and subclinical actinic keratoses (areas that may not yet be detectable by the naked eye), offering a comprehensive approach to sun-damage repair.
Why PDT Is an Effective Option
Photodynamic Therapy provides several key advantages:
- Treats multiple lesions at once, especially helpful for widespread sun-damage
- Targets early, precancerous changes before they become more serious
- Promotes overall skin rejuvenation
- Minimal downtime compared with surgical options
- Selective activation minimizes damage to healthy tissue
Our dermatologists tailor the protocol based on the extent of sun damage, skin type, and cosmetic goals.
What to Expect During Treatment
Your PDT session typically involves:
- Skin evaluation to determine the targeted areas
- Application of a photosensitizing agent to the sun-damaged regions
- Absorption period, allowing the medication to penetrate
- Light activation, which stimulates the therapeutic reaction
The light treatment may feel warm, and some patients experience mild tingling. Most patients tolerate the procedure well, and sessions are generally completed in less than an hour.
After treatment, treated areas may appear red or slightly crusted, a normal part of the healing process.
Recovery & Aftercare
Following PDT, your skin will be more sensitive to sunlight for at least 48-72 hours, so strict sun protection is essential. Your dermatologist will provide specific aftercare instructions, which may include:
- Avoiding sun exposure and direct UV light
- Using gentle cleansers and prescribed moisturizers
- Applying broad-spectrum sunscreen daily
Most patients see improvement in texture and tone within a few weeks as treated cells are shed and healthier skin emerges.
PDT Home Care Instructions
Day of Treatment
You may apply an ice pack or cool water to the treated areas if needed. This will help keep the area cool and alleviate any discomfort as well as help keep swelling down.
Use Advil or Tylenol for discomfort if needed.
Protect yourself from the sun! Use a wide brimmed hat and sunscreen with an SPF of 30 or greater. Your skin will be VERY sensitive to the light for 48 hours. Stay indoors with as little light exposure as possible. You may leave the house after 48 hours. Make sure you are applying sunscreen frequently during your healing process.
Day 2-7
You may shower the day after your treatment. Continue with steps above. The discomfort usually subsides between 48-72 hours following the treatment.
If blisters form, you should soak the areas with a solution of 1 teaspoon of white vinegar and 1 cup of cold water. Ice should be applied directly over vinegar soaks. Soak for 20 min. Pat the area dry and apply the Calming Cream from our office, (or Aquaphor and Hydrocortisone). Follow this step every 4-6 hours during the hours you are awake.
Re-apply Aquaphor or Calming Cream as needed. The treated area will be dry and tight. Keep using moisturizer to help hydrate your skin.
Day 7-14
You may begin using make-up or shaving once the crusting, if any, has healed. This usually occurs 5-10 days following the treatment.
Avoid getting any sun 2 weeks after the treatment. The treated area will be very photosensitive to sun exposure and pigment changes may occur. Re-apply your sunscreen at least 2 times a day.
Please call our office if the redness worsens, becomes painful, or does not improve after two weeks.
Who Is a Good Candidate for PDT?
Photodynamic Therapy is often recommended for adult patients who:
- Have multiple actinic keratoses
- Show signs of widespread sun damage
- Prefer a non-surgical treatment option
- Want preventive therapy to reduce future skin cancer risk
A consultation with our dermatologists ensures PDT is the right choice for your skin type and history.
Frequently Asked Questions About PDT & AK
Does PDT hurt?
A mild tingling or warmth is common during light activation, but most patients find it tolerable. Cooling measures and breaks can increase comfort.
How many treatments are needed?
Many patients see benefit with one treatment, but your dermatologist may recommend a series based on lesion density and response.
Can PDT prevent skin cancer?
PDT treats precancerous changes and can reduce the risk of progression to squamous cell carcinoma, but ongoing sun protection and regular skin exams remain essential.
Is there downtime after treatment?
There is minimal downtime. You can generally resume normal activities the same day, but sun avoidance is critical in the first 48–72 hours.
Is PDT safe for all skin types?
PDT is safe for many skin types, but individual suitability will be determined during your consultation.
Protect & Renew Your Skin
If sun-damaged skin and actinic keratoses concern you, Pure Dermatology Cosmetic and Hair Center in Newport Beach, Orange County offers expert Photodynamic Therapy to treat early precancerous changes and support healthier skin long-term.
Call or Text Today to Schedule Your Consultation